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[virus] Lung Samples From 1918 Show a Pandemic Virus Mutating‘The team was able to recover a complete flu-virus genome from the 17-year-old girl’s lung tissue—only the third ever found. The two other full 1918 flu genomes both came from the United States, from the lungs of a woman buried in Alaska and from a paraffin-wax-embedded lung sample of a soldier who died in New York. With another genome in hand, the researchers moved to investigate how they differed. Several changes showed up in the flu’s genome-replication machinery, a potential evolutionary hot spot because better replication means a more successful virus. The team then copied just the replication machinery of the 17-year-old’s virus—not the entire virus—into cells and found it was only half as active as that of the flu virus found in Alaska.’

Did the 1918 Flu Virus Mutate?

This entry was posted on Tuesday, May 25th, 2021 at 10:12 am and is filed under COVID-19, disease.

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